It took until the second day of the 2008 MLB first-year player draft for the names of D-III players to be announced, but the names came. Twenty players who played baseball in the 2008 season in the NCAA's Division III were selected in the MLB draft, comparable to the 19 players selected last season.
Ryan Kulik, Rowan was selected by the St. Louis Cardinals in the eighth round, No. 245 overall, while Chapman's Kurt Yacko went to the Colorado Rockies minutes later, at No. 257. Both pitchers were highly touted prospects and finished the season on the D3baseball.com All-American team.
It would be nine rounds later for the third selection as the
Cincinnati Reds selected third baseman Frank Pfister of Emory with the 506th selection. Following the Pfister selection were Dominican right-hander Mike Eifel (by San Francisco, 627th overall) and St. Norbert shortstop Adam Frost (Detroit, 643) in the 21st round.
The draft reached the halfway mark with six selection. The last selection in the first half was Keystone's third baseman, Nelson Gomez, selected by Arizona in the 24th round, 738th overall.
The 26th round selection of LHP Shane Wolf, Ithaca by Houston started the second half of the MLB draft. Wolf was followed by Los Angeles Angel's selection (27th round), RHP Tim Kiely, Trinity (Conn.) and Cincinnati's selection (34th), LHP Bryan Gardner, Ithaca. The tenth selection was also the first outfielder as Mike Vass, Chapman was selected by the Milwaukee Brewewrs in the 35th round.
Ten pitchers were drafted and nine position players. Despite the availability of two high profile catchers in Doug Coe, UW-Stevens Point and Mike Zaccardo, Cortland State, no catchers from a D-III school were drafted.
The complete draft list:
| Overall | Player, School | Position | Team (round) |
| 245 | Ryan Kulik, Rowan | LHP | St Louis (8) |
| 257 | Kurt Yacko, Chapman | RHP | Colorado (8) |
| 506 | Frank Pfister, Emory | 3B | Cincinnati (17) |
| 627 | Mike Eifel, Dominican | LHP | San Francisco (21) |
| 643 | Adam Frost, St, Norbert | SS | Detroit (21) |
| 738 | Nelson Gomez, Keystone | 3B | Arizona (24) |
| 782 | Shane Wolf, Ithaca | LHP | Houston (26) |
| 829 | Tim Kiely, Trinity (Conn.) | RHP | Los Angeles AL (27) |
| 1019 | Bryan Gardner, Ithaca | LHP | Cincinnati (34) |
| 1058 | Mike Vass, Chapman | OF | Milwaukee (35) |
| 1088 | Evan Bronson, Trinity (Texas) | LHP | Milwaukee (36) |
| 1132 | Thomas DeBenedetto, Trinity (Conn.) | SS | Boston (37) |
| 1136 | Thomas Phelps, Whittier | RHP | Baltimore (38) |
| 1141 | Ronnie Labrie, Lynchburg | 3B | Washington (38) |
| 1209 | Nate Nelson, Worcester State | 1B | Toronto (40) |
| 1368 | Dean Laganosky, Haverford | OF | Cleveland (45) |
| 1392 | Dan Kauffman, Juniata | 1B | Arizona (46) |
| 1421 | Ryan Flannery, FDU-Florham | RHP | New York AL (47) |
| 1435 | Brett Holland, Texas-Tyler | RHP | Oakland (48) |
| 1452 | Zachary Foster, Pitt-Bradford | RHP | Pittsburgh (49) |
Players that were not drafted are free to sign free agent contracts and as soon as the MLB draft was over, undrafted players like
D3baseball.com's pitcher of the year Kenny Moreland started the free agent signing season.
There were two players drafted who transfered from a D-III to an other school. UC Santa Barbara's Chuck Huggins, who transferred from Trinity (Texas) after his sophomore year, was drafted by the Toronto Blue Jays in the 23rd round. Tim Matthews, who played one year for Texas-Tyler, was drafted out of Baylor by Colorado in the 27th round.
In 2007
19 D-III players were drafted starting with Zimmermann in the second round and ending with Rob Sanzillo, Johns Hopkins in round 46.
